Managing Inflammation after Spinal Cord Injury through Manipulation of Macrophage Function

Table 1

Inflammatory (classical) and resident (nonclassical) monocytes.

	Classical/inflammatory	Nonclassical/patrolling	References
Surface markers	Mouse: CD115^+, Ly6C^++, CD43^+, CCR2^hi, CD62L^+, CX3CR1^lo	Mouse: CD115^+, Ly6C^−, CD43^++, CCR2^lo, CX3CR1^hi	[22–24, 108–110]
	Human: CD14^++, CD16^−	CD14^+, CD16^++, MHCII
Functions	Steady state precursor for Ly6C^−; Infiltrate into inflamed tissues	Patrolling and enter noninflamed tissue	[21, 111]