Research Article

Presynaptic Glycine Receptors Increase GABAergic Neurotransmission in Rat Periaqueductal Gray Neurons

Figure 4

Effect of TTX on glycine-induced increase in sEPSC frequency. (a) Typical traces of glutamatergic sEPSCs observed during the application of 100 μM glycine in the absence (upper) and presence (lower) of 300 nM TTX. (b) Glycine-induced changes in frequency (A) and amplitude (B) of sEPSC in the absence and presence of TTX. Note that the glycine-induced facilitation of sEPSC frequency was completely suppressed by TTX. Each column was the mean and SEM from 7 neurons. ** ; n.s.: not significant.
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(a)
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(b)