Hippocampal Neurogenesis and Antidepressive Therapy: Shocking Relations

<table>(a) Detection of microglia in the granular layer (GL) of a 2-month-old mouse based on the expression of Iba1 (white) (ML: molecular layer). Scale bar: 50 <i>μ</i>m. (b) Microglia volume was estimated according to the percentage of the surface covered by Iba1<sup>+</sup> labelling in the granular layer of 2- and 20-month-old mice following ECS or sham treatment. Two-way ANOVA revealed upon ECS a significant increase of Iba1-labeled surface in the dentate gyrus of both age groups (<svg height="11.375" id="M14" style="vertical-align:-0.17555pt" version="1.1" viewbox="0 0 75.025002 11.375" width="75.025002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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Neural Plasticity

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Figure 4

Figure 4: Hippocampal Neurogenesis and Antidepressive Therapy: Shocking Relations 