Nociceptive Neurons Differentially Express Fast and Slow T-Type Ca²⁺ Currents in Different Types of Diabetic Neuropathy

Table 1

Parameters of fast and slow T-currents in NTCN neurons.

Control		𝐶, pF		T-current parameters at −45 mV
				Peak current; density, pA/pF		Time constant of; activation, ms		Time constant of; inactivation, ms
		Fast	Slow	Fast	Slow	Fast	Slow	Fast	Slow
		18.8±1.0	12.8±1.5	2.8±0.3	5.2±0.5	6.6±0.6	7.2±0.8	26±2	76±5
Diabetes	Hyperalgesia	15.5±1.4		4.4±0.4		5.0±0.9		27±4
	Hypoalgesia	17.9±1.0	17.7±1.0	2.6±0.4	2.0±0.6	7.7±1.6	6±1	27±3	66±4
	Normalgesia	2.6±2.2	13.3±1.0	2.5±0.5	1.9±0.5	6.1±0.7	3.2±0.3	23±2	66±8