Neurexin-Neuroligin Synaptic Complex Regulates Schizophrenia-Related DISC1/Kal-7/Rac1 “Signalosome”

Figure 4

NX1β increases the mRNA level of the immediate early gene c-fos. Cortical neurons were grown for 8 days and treated with different concentrations of recombinant NRXN1b for 2 h. Total RNA was isolated, and mRNA levels were assessed using RT-PCR. The results from experiments are expressed as a percentage ± SEM. , compared with the untreated control set at 100%.