In Vitro Studies of Neuronal Networks and Synaptic Plasticity in Invertebrates and in Mammals Using Multielectrode Arrays

<div>(a) Schematic representation of a field-effect transistor (FET). (b) Example of Helix neurons 24 hours after plating on MEA. Scale bar is 50 μm. (c) Cortical neurons after 24 days in vitro coupled to a MEA. Scale bar is 15 μm. (d) Extracellular action potentials recorded by a MEA relative to B2 (top) and C1 (bottom) Helix neurons. (e) Typical bursting activity of a cortical network recorded by a MEA.</div>

Neural Plasticity

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Figure 1

Figure 1: In Vitro Studies of Neuronal Networks and Synaptic Plasticity in Invertebrates and in Mammals Using Multielectrode Arrays