Reorganization of Anatomical Connectome following Electroconvulsive Therapy in Major Depressive Disorder

Figure 1

Significant differences in anatomical connection between post-ECT and pre-ECT. Nodes (individual ROIs) were differently colored according to the six anatomical modules listed in Table 2. Undirected edges were differently colored according to the significantly larger connection (). Nodes and edges are presented on inflated surface maps by BrainNet Viewer (http://www.nitrc.org/projects/bnv) [21]. Scatter-plot indicated the changed connection (post-ECT − pre-ECT) showing significant correlation with the HAMD reduction (pre-ECT − post-ECT).