Alterations of the Ceramide Metabolism in the Peri-Infarct Cortex Are Independent of the Sphingomyelinase Pathway and Not Influenced by the Acid Sphingomyelinase Inhibitor Fluoxetine

Figure 3

Sphingomyelinase activity is not altered in the peri-infarct cortex. (a) ASM activity and (b) NSM activity. Sphingomyelinase activity was measured at different time points by an enzyme activity assay with radioactive labeled sphingomyelin. Differences between sham and PT group were analyzed using Student’s unpaired two-tailed -test. Data are presented as means ± SD; n.s., nonsignificant; = 5–10/group.

(a)

(b)