Research Article
Preclinical Evidences for an Antimanic Effect of Carvedilol
Figure 5
Levels of malondialdehyde (MDA), a lipid peroxidation marker, in the prefrontal cortex (PFC) and striatum (ST) of mice submitted to the prevention (a) and reversal (b) treatments. Data were analyzed by one-way ANOVA followed by Student-Newman-Keuls post hoc test. Values are expressed as mean ± SEM (6–8 animals/group). ∗ versus Sal + Sal; # versus Sal + LDX or LDX + LDX. CVD: carvedilol; LDX: lisdexamfetamine; Sal: saline; VAL: valproate.
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