Review Article

Involvement of Adult Hippocampal Neurogenesis in Learning and Forgetting

Figure 2

Potential influences of adult neurogenesis on new memory formation and old memory clearance. Increased neurogenesis improves pattern separation when acquiring new information with much overlap and yet accelerates clearance of old memories. Conversely, decreased neurogenesis facilitates the temporal storage of short-term memory and thus enhances memory retrieval in the hippocampus, yet aggravating memory interference of similar events during new information acquisition.