Sensory Deprivation during Early Postnatal Period Alters the Density of Interneurons in the Mouse Prefrontal Cortex

Figure 4

Sensory deprivation changes PV neuron density in the PFC. The density of PV neurons in the PL (a, b), IL (c, d), and dAC (e, f). PV neuron density at P28 (a, c, e) and P58 (b, d, f) in each area are shown. (a)-(b) The density of PV neurons was increased in L5/6 by sensory deprivation at P56. (c)-(d) The density of PV neurons in L2/3 was decreased at P28 by sensory deprivation, but it was increased in L5/6 at P56. (e)-(f) The density of PV neurons in L5/6 was increased with sensory deprivation at both P28 and P56. Data are expressed as mean density S.E.M. ( per group). Abbreviations are the same as in Figure 4. compared with intact mice.

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