Extrinsic and Intrinsic Regulation of Axon Regeneration by MicroRNAs after Spinal Cord Injury

Table 1

Differentiated expression of microRNAs in different spinal cord injury models.

Expression patterns	Spinal cord injury model		Reference
	Ischemia-reperfusion injury	Contusion injury
Upregulation	miR-204, miR-365, miR-323, miR-672, miR-760-5p, miR-376b-5p, miR-369-5p, miR-133a, miR-505, miR-466d, miR-132, miR-665, miR-463	miR-1, miR-15b, miR-20a, miR-20b-5p, miR-21, miR-30a, miR-31, miR-92a, miR-92b, miR-93, miR-98, miR-106b, miR-145, miR-146b, miR-152, miR-199a-3p, miR-203, miR-206, miR-214, miR-221, miR-223, miR-290, miR-333, miR-374, miR-378, miR-672, miR-674-5p, miR-872, miR-17, miR-146a, miR-124, miR-486	[15, 23, 24, 112, 113]
Downregulation	miR-210, miR-146a, miR-199a-3p	miR-30b-5p, miR-30c, miR-30d, miR-34a, miR-129, miR-137, miR-138, miR-219-2-3p, miR-219-5p, miR-323, miR-325-3p, miR-338, miR-379, miR-384-5p, miR-495, miR-543, miR-708, miR-125-3p, miR-126, miR-let-7b, miR-129-1, miR-129-2, miR-129-3p, miR-342	[21, 36, 37, 113, 114]
Early: upregulation; late: downregulation		miR-99a, miR-100, miR-103, miR-107, miR-124, miR-127, miR-128, miR-154, miR-181a, miR-434, miR-487b, miR-124a, miR-133a, miR-133b, miR-45	[15, 23, 90]

MicroRNAs are significantly upregulated at 4 hours and then downregulated at 7 days after SCI.