A Novel Nonsense Mutation of POU4F3 Gene Causes Autosomal Dominant Hearing Loss

Table 1

Variants of POU4F3 related to DFNA 15.

Description	Exon	Amino acid change	Type of variant	Ethnicity	Reference
c.884del8	2	Ile295Thrfs5	Frameshift	Jewish	Vahava et al. (1998) [14]
c.668T>C	2	Leu223Pro	Missense	Dutch	Collin et al. (2008) [10]
c.865C>T	2	Leu289Phe	Missense	Dutch	Collin et al. (2008) [10]
c.662del14	2	Gly221Glufs77	Frameshift	Korean	Lee et al. (2010) [13]
c.694G>A	2	Glu232Lys	Missense	Korean	Baek et al. (2012) [9]
c.977G>A	2	Arg326Lys	Missense	Korean	Kim et al. (2013) [12]
c.603_604delGG	2	Val203Aspfs11	Frameshift	Chinese	Yang et al. (2013) [16]
Deletion of entire gene	2		Deletion	Brazilian	Freitas et al. (2014) [11]
c.491C>G	2	Pro164Arg	Missense	Chinese	Wei et al. (2014) [15]
c.337C>T	2	Gln113	Nonsense	Chinese	This study