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Neural Plasticity
Volume 2016, Article ID 3760702, 15 pages
http://dx.doi.org/10.1155/2016/3760702
Research Article

Cellular Zinc Homeostasis Contributes to Neuronal Differentiation in Human Induced Pluripotent Stem Cells

1Institute for Anatomy and Cell Biology, Ulm University, 89081 Ulm, Germany
2Department of Anaesthesiology, University of Ulm, 89081 Ulm, Germany
3Institute of Neuroanatomy, Eberhard Karls University of Tübingen, 72074 Tübingen, Germany
4WG Molecular Analysis of Synaptopathies, Neurology Department, Neurocenter of Ulm University, 89081 Ulm, Germany

Received 23 February 2016; Accepted 24 March 2016

Academic Editor: Bruno Poucet

Copyright © 2016 Stefanie Pfaender et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The Supplementary Material shows the quantitative evaluation of mRNA expression levels of selected zinc homeostasis and the zinc dependent SHANK genes under elevated zinc conditions (Figure S1) and the morphological analysis of motor neurons derived from iPS cells grown under control conditions and under altered zinc levels (Figure S2).

  1. Supplementary Material