Blockade of Toll-Like Receptors (TLR2, TLR4) Attenuates Pain and Potentiates Buprenorphine Analgesia in a Rat Neuropathic Pain Model
Levels of allodynia ((a); von Frey’s test) and hyperalgesia ((b); cold plate test) measured on 2nd, 7th, and 14th days after chronic constriction injury (CCI) in rats. The data are presented as the mean ± SEM (11–25 rats per group). Intergroup differences were analyzed using one-way ANOVA followed by Bonferroni’s multiple comparisons test. indicates a significant difference versus the INTACT group.