Research Article

Altered Effective Connectivity of Hippocampus-Dependent Episodic Memory Network in mTBI Survivors

Figure 2

Causal influence of effectively connected episodic memory network in normal controls and mTBI survivors. (i) Connection density in normal controls and mTBI was not significantly different; (ii) significant causal interaction mainly existed between ROIs in the left hemisphere in normal controls, while mTBI survivors presented significant cross-hemisphere connection originating from the right hemisphere; (iii) nodes of source hubs (flow-out hubs), target hubs (flow-in hubs), and network hubs were displayed by different colors, but only the network hub color was presented if their function overlapped (a, c); (iv) significant causal interactions from nodes in -axis to nodes in -axis among all possible causal interactions were presented in (b, d); (v) relative strengths of path weights (in arbitrary units) were indicated by the width of lines; (vi) IFG:inferior frontal gyrus; MeFG: medial frontal gyrus; MTG-middle temporal gyrus; ITG: inferior temporal gyrus; STG-: superior temporal gyrus; FG: fusiform; HC: hippocampus; PHG: parahippocampal gyrus; ACC: anterior cingulate cortex; PCC: posterior cingulate cortex.
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