Research Article
Restoring Spinal Noradrenergic Inhibitory Tone Attenuates Pain Hypersensitivity in a Rat Model of Parkinson’s Disease
Figure 3
Change of NE, 5-HT, and dopamine (DA) content in the lumbar spinal cord in the 6-OHDA-lesioned rat model. Samples were collected at the 5th week after 6-OHDA-lesion and NE (a), 5-HT (b), and DA (c) content in the lumbar spinal cord were analyzed by HPLC. Compared to the sham group, the NE content significantly decreased in the 6-OHDA-lesioned animals ( compared to the sham group, for each group). 5-HT and DA content did not significantly change between the 6-OHDA-treated group and sham control group ( compared to the sham group, for each group).
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