Review Article

Coping with the Forced Swim Stressor: Towards Understanding an Adaptive Mechanism

Table 1

The effect of a single dose of 25 mg/kg of imipramine administered one hr before or 15 min after training on day 1 on rat mobility in the forced swim test.

Injection timeNo. of impulses, day 1 % no. of impulses, day 2

Saline7409.85 ± 48.7942.63 ± 11.50
15 min after7420.14 ± 45.9394.39 ± 8.38
1 hour before6421.66 ± 39.7593.06 ± 16.44

Statistical significance (at < .01) with respect to the saline group.
Adapted and reprinted from De Pablo et al. [9] with permission from Elsevier B.V.