Drosophila Torsin Protein Regulates Motor Control and Stress Sensitivity and Forms a Complex with Fragile-X Mental Retardation Protein

Figure 7

Gene ontology and interacting gene analysis for 22 dysregulated proteins in DTor mutant brains. (a-b) Twenty-two dysregulated proteins were allocated according to their biological processes (a) or pathways (b). Protein-protein interactions among them were predicted using STRING DB (c). The size of each node is correlated with the amount of structural information associated with each protein. The width of lines represents the confidence score of precalculated protein-protein interaction [16, 17].

(a) Gene ontology: biological process

(b) Gene ontology: panther pathway

(c) STRING analysis of dysregulated proteins