Carbachol-Induced Reduction in the Activity of Adult Male Zebra Finch RA Projection Neurons

Figure 4

Effects of 30 μM carbachol on the intrinsic properties of RA projection neurons. (a) Representative AP recordings in response to a depolarizing pulse before and during carbachol application. (b) AHP peak amplitude was significantly increased in the presence of carbachol (). (c) AHP time to peak was significantly increased in the presence of carbachol (). (d) Voltage responses of a neuron to a series of hyperpolarizing current steps before, during, and after carbachol application. (e) The current-voltage curves showed that there was a significant change in the slope by carbachol application (), indicating carbachol had an effect on membrane input resistance. (f) Membrane input resistance was significantly decreased in the presence of carbachol (). means , means , paired test.

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