Assessment of the Central Effects of Natural Uranium via Behavioural Performances and the Cerebrospinal Fluid Metabolome

Figure 3

Locomotor activity and spatial working memory of male rats exposed to 1.5, 10, or 40 mg⋅L⁻¹ NU from birth for 9 months. (a) shows the number of arm entries in the Y-maze and reflects locomotor activity. (b) shows the alternation between arms, expressed as a percentage (%), in the Y-maze and reflects spatial working memory. The data are presented as mean ± SEM; for each group; NU: natural uranium; , significant difference from control; , significant difference from 1.5 mg⋅L⁻¹ NU.

(a)

(b)