Aromatase Expression in the Hippocampus of AD Patients and 5xFAD Mice

Figure 3

Various types of aromatase first exons were expressed in the hippocampi from patients without neurological diseases and patients with AD. RT-PCR using primer sets specific for different first exons of aromatase mRNA showed that several different promoters, namely, I.f, PII, I.3, and I.6, regulate aromatase expression in the hippocampus. The respective first exons were expressed in healthy hippocampi as well as in hippocampi from patients with AD. The numbers given for each sample refer to Table S1 (sample numbers 11–18).