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Neural Plasticity
Volume 2016, Article ID 9803165, 9 pages
Research Article

Functional Integration between Salience and Central Executive Networks: A Role for Action Video Game Experience

1Key Laboratory for NeuroInformation of Ministry of Education, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China
2ARC Centre of Excellence in Cognition and Its Disorders, Macquarie University, Sydney 2109, NSW, Australia

Received 27 April 2015; Revised 2 September 2015; Accepted 2 September 2015

Academic Editor: Malgorzata Kossut

Copyright © 2016 Diankun Gong et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Action video games (AVGs) have attracted increasing research attention as they offer a unique perspective into the relation between active learning and neural plasticity. However, little research has examined the relation between AVG experience and the plasticity of neural network mechanisms. It has been proposed that AVG experience is related to the integration between Salience Network (SN) and Central Executive Network (CEN), which are responsible for attention and working memory, respectively, two cognitive functions essential for AVG playing. This study initiated a systematic investigation of this proposition by analyzing AVG experts’ and amateurs’ resting-state brain functions through graph theoretical analyses and functional connectivity. Results reveal enhanced intra- and internetwork functional integrations in AVG experts compared to amateurs. The findings support the possible relation between AVG experience and the neural network plasticity.