In Sickness and in Health: Perineuronal Nets and Synaptic Plasticity in Psychiatric Disorders

Figure 2

Decreased CS-6 in the amygdala of subjects with schizophrenia. In the amygdala of control subjects, CS-6(3B3)-labeled PNNs and glial cell clusters are distributed in the lateral (LN), basal (BN), accessory basal (AB), and corticomedial (CO-Me) nuclei (a, b). In subjects with schizophrenia, marked decreases of PNNs and glia cell clusters immunolabeled for CS-6(3B3) were observed in the amygdala of (c, d) [55]. ECx: entorhinal cortex. HP: hippocampus.