Figure 10: AAV-KLF7 promotes DPSN axonal plasticity and induced synapse formation with motor neurons at the caudal spinal cord. (a) Contact between motoneurons (CTB retrogradely labeled, red) and DPSN axons (BDA-labeled, green) and synapse formation (synaptophysin-labeled, purple) are shown. Block indicates the new synapses formation (white) between DPSN axons and motoneurons. Quantitative analyses of the motor neuron targeted CTB-labeled axons (b), BDA relative density (c), and SYP density per motoneuron per section (d) at the caudal spinal cord. mice/group. , , and . NS: not significant. One-way ANOVA, Tukey’s post hoc test. Scale bars: 100 μm.