Figure 9: AAV-KLF7 significantly improves DPSN axonal plasticity around the lesion. Five weeks following contusion injury, (a-b) representative immunohistochemical stainings for GFAP (green) and BDA (labeling DPSN axons, red) and nuclear staining (DAPI, blue) surrounding the epicenter of SCI + AAV-GFP and SCI + AAV-KLF7 groups are presented. Quantitative analyses of the GFAP relative density (c) and BDA relative density (d) around the lesion area. mice/group. Student’s t-tests; green indicates SCI + AAV-GFP control; red indicates SCI + AAV-KLF7. . NS: not significant. Scale bars: 300 μm or 100 μm.