Soluble Epoxide Hydrolase Inhibitor and 14,15-Epoxyeicosatrienoic Acid-Facilitated Long-Term Potentiation through cAMP and CaMKII in the Hippocampus

<div>TPPU- and 14,15-EET-facilitated HFS-induced LTP are blocked by NR2B antagonist in the hippocampus. (a) Effects of TPPU (0.1 <i>μ</i>M) and 14,15-EET (30 nM) on the enhancement of HFS-induced LTP. (b) Bar chart comparing the effects of TPPU and 14,15-EET after potentiation for 10 min and 60 min. (c) Administration of Ro 25-6981 (1 <i>μ</i>M) blocked TPPU- and 14,15-EET-enhanced HFS-induced LTP. (d) Bar chart showing that Ro 25-6981 blocked TPPU- and 14,15-EET-enhanced HFS-induced LTP after potentiation for 10 min and 60 min. 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Neural Plasticity

fig2

Figure 2

Figure 2: Soluble Epoxide Hydrolase Inhibitor and 14,15-Epoxyeicosatrienoic Acid-Facilitated Long-Term Potentiation through cAMP and CaMKII in the Hippocampus 

Figure 2 | Soluble Epoxide Hydrolase Inhibitor and 14,15-Epoxyeicosatrienoic Acid-Facilitated Long-Term Potentiation through cAMP and CaMKII in the Hippocampus 