Distinct Pattern of Microgliosis in the Olfactory Bulb of Neurodegenerative Proteinopathies

Figure 8

Increased number of cells expressing PSA-NCAM in the GLOM of PDD/DLB and FTLD patients. The number of cells expressing the immature neuronal marker PSA-NCAM was increased in the GLOM from PDD/DLB and FTLD cases, but not in AD patients, while in the GCL and the OT the number of cells was not altered compared to controls. (a) Representative images of cells expressing PSA-NCAM in all regions analyzed from controls, AD, PDD/DLB, and FTLD cases. Quantification presented in (b). 1-way ANOVA, Kruskal-Wallis post hoc test, . Scale bar represents 50 μm.

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