Hippocampal Regulation of Postsynaptic Density Homer1 by Associative Learning

Figure 5

In the retrieval and extinction of contextual fear memory, rats displayed robust conditioned freezing and an extinguished response after long recall (10 min). Retrieval and extinction training took place 48 h after conditioning. Control “no recall” animals were conditioned and culled 48 h afterwards. Rats were culled 30 min or 2 h after retrieval and extinction for in situ hybridization. (30 min), (2 h), or (no recall) per group. Data represented by mean ± SEM percent freezing.