Attenuated Late-Phase Arc Transcription in the Dentate Gyrus of Mice Lacking Egr3
Table 1
Mean number of cells per animal counted across the hippocampal formation.
Genotype
Group
Region
Proximal CA11
Distal CA11
CA3a2
CA3c2
DGSP
DGIP
WT
Caged
297.4 ± 18.3
353.8 ± 11.2
168.5 ± 15.6
224.6 ± 20.8
1782.5 ± 382.7
1424.3 ± 269.3
0
330.8 ± 14.3
337. 6 ± 12.1
202.5 ± 9.2
157.0 ± 9.6
1620.6 ± 330.5
1213.9 ± 386.7
60
305.7 ± 20.2
285.4 ± 15.2
189.1 ± 8.7
212.0 ± 18.4
1662.5 ± 263.3
1487.5 ± 283.2
240
263.1 ± 13.3
335.1 ± 9.6
154.5 ± 11.1
294.0 ± 12.1
1726.7 ± 280.9
1322.2 ± 279.1
480
305.4 ± 11.4
319.0 ± 19.1
209.8 ± 9.0
252.8 ± 15.0
1905.2 ± 324.9
1610.8 ± 253.2
Egr3−/−
Caged
360.8 ± 14.9
309.6 ± 19.0
135.5 ± 5.4
189.9 ± 13.6
1980.2 ± 324.9
1380.1 ± 254.8
0
348.2 ± 23.1
297.3 ± 18.1
180.8 ± 15.8
150.7 ± 9.3
1816.9 ± 317.4
1554.7 ± 262.6
60
315.3 ± 16.3
347.0 ± 18.6
101.5 ± 18.0
240.8 ± 16.8
1722.1 ± 296.8
1442.5 ± 256.5
240
415.1 ± 21.8
326.3 ± 17.8
216.8 ± 19.8
217.2 ± 9.0
1835.6 ± 309.1
1322.2 ± 234.6
480
227.9 ± 27.7
354.9 ± 14.0
175.4 ± 7.4
194.0 ± 9.4
2015.6 ± 314.3
1493.3 ± 261.9
1In a transverse section of the hippocampus, proximal CA1 is the region closest to CA2, while distal CA1 is closest to the subiculum (see Figure 1). 2In a transverse section of the hippocampus, CA3a is the region closest to CA2, while CA3c is closest to the DG (see Figure 1).
