Evidence of Presynaptic Localization and Function of the c-Jun N-Terminal Kinase

Figure 6

D-JNKI1 treatment reduced the frequency of mEPSCs in mice cortical slices. (a) Representative traces of mEPSCs recorded from cortical slices under control condition or after incubation with D-JNKI1n for 1 hr. (b-c) Bar graph (mean ± SEM) showing the mEPSC frequency (b) and amplitude (c) obtained in the first 5 min of recordings from control () and D-JNKI1-treated () cortical neurons. CTR versus D-JNKI1 treatment: Student’s t-test, n =8. Data are shown as mean +/− SEM.

(a)

(b)

(c)