Corticospinal Tract Wiring and Brain Lesion Characteristics in Unilateral Cerebral Palsy: Determinants of Upper Limb Motor and Sensory Function

Table 1

Contingency table (count and percentage, descriptive statistics) of the occurrence of lesion timing, location, and extent according to the CST wiring.

			CST wiring			value
			Contralateral	Bilateral	Ipsilateral
Timing
Lesion timing^¥	PV	(%)	15 (88.2%)	8 (50%)	11 (57.9%)	0.04
	CSC		2 (11.8)	8 (50%)	8 (42.1%)
Location
PLIC^¥	Not affected	(%)	8 (47%)	1 (6%)	0 (0%)	<0.001
	Affected		9 (53%)	15 (94%)	19 (100%)
Basal ganglia and thalamus^◊		Me (p25–p75)	0 (0–1)	1.50 (0–2.50)	1 (1–2)	0.006^a,b
Frontal lobe^◊		Me (p25–p75)	1 (1–1)	1.50 (1–2.25)	1 (1–1.50)	0.004^a,b
Parietal lobe^◊		Me (p25–p75)	2 (1–2)	2 (1.25–3)	2 (2–2.50)	0.09
Extent
Ipsilesional extent^○		(SD)	5.18 (3.07)	8.38 (3.95)	9.05 (3.27)	0.004^a,b

CST: corticospinal tract; PV: periventricular; CSC: corticosubcortical; PLIC: posterior limb of the internal capsule. ^¥Chi-square statistic. ^§Fisher’s exact test. ^◊Kruskal-Wallis test. ^○ANOVA. ^aContralateral vs. ipsilateral. ^bContralateral vs. bilateral.