Action Observation Treatment Improves Upper Limb Motor Functions in Children with Cerebral Palsy: A Combined Clinical and Brain Imaging Study
(a) Graphic representation of the fMRI experimental paradigm, alternating manipulation of a simple object (a sphere), and manipulation of complex objects. (b) Clusters of activations transposed on sections from standard pediatric brain (ANTS) before treatment (T1), when comparing manipulation of complex objects versus manipulation of a sphere. Cases and controls are taken as a whole group, . Note that at T1, no activation was present when directly comparing cases versus controls. (c) After treatment (T2), direct comparison between cases and controls shows increased activations in frontal and parietal areas known to be involved in hand-object interactions, . Clusters of activations transposed on sections from standard pediatric brain (ANTS), as in (b).