Research Article

Repulsive Environment Attenuation during Adult Mouse Optic Nerve Regeneration

Figure 1

Optic nerve regeneration. (a–d) CTB labeling (red) and nuclear staining (blue) two weeks after optic nerve injury; (a and b) optic nerve from the Crush-only group exhibiting no CTB+ axons (red) beyond injury site; (c and d) optic nerve from the Regenerating group showing full-length axon regeneration; (e–g) CTB (red) and nuclear labeling (blue) showing different levels of reinnervation of the visual nuclei twelve weeks after optic nerve injury. (e) CTB+ axons at the suprachiasmatic nucleus; (f) CTB+ fibers at the lateral geniculate nucleus; (g) CTB+ axons at the superior colliculus. per group. (a–g) Scale bars: 50 μm.
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