Differential Corticomotor Excitability Responses to Hypertonic Saline-Induced Muscle Pain in Forearm and Hand Muscles

Figure 1

Experimental design. Participants joined two experimental sessions separated by at least 48 hours. In session one, experimental pain was induced by injection of hypertonic saline into the ECR muscle and in session two the FDI muscle was injected. The procedure for both sessions was identical with the only difference being the optimal scalp position determined for either the ECR or FDI muscle. ECR: extensor carpi radialis; FDI: first dorsal interosseus; RMT: resting motor threshold; TMS: transcranial magnetic stimulation.