Research Article

Chronic Unexpected Mild Stress Destroys Synaptic Plasticity of Neurons through a Glutamate Transporter, GLT-1, of Astrocytes in the Ischemic Stroke Rat

Figure 1

(a) Schematic of the experimental designs. (b) Ceftriaxone reversed the decrease of GLT-1 mRNA in the hippocampus of the CUMS-induced model rats on the 28th day and the 42nd day. (c) Representative western blotting pictures showed proteins of GLT-1 and synaptophysin (SYP, SYN) in the hippocampus on the 21st/28th/42nd day. (d) Ceftriaxone reversed the decrease of GLT-1 protein in the hippocampus of the CUMS-induced model rats at the three time points. (e) SYN decreased on the 42nd day and then was reversed by ceftriaxone. , , , , one-way ANOVA (Tukey), .
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