The Modulatory Effect of Cerebrovascular Burden in Response to Cognitive Stimulation in Healthy Ageing and Mild Cognitive Impairment

Table 1

Demographic and neurostructural differences between the healthy ageing and MCI groups.

	Mean (SD)		difference
	Healthy ageing	MCI
Demographic variables
Age	67.64 (7.35)	73.86 (5.21)
Years of education	10.52 (4.12)	8.50 (3.65)
Gender (m/f)	9/16	12/10
APOE ε4 carriers (, %)	5 (20%)	7 (33.3%)
Neurostructural volumes (ml)
Grey matter	586.12 (53.46)	532.88 (51.07)
White matter	435.30 (42.87)	423.62 (55.46)
CSF	351.71 (77.72)	451.34 (96.46)
Total intracranial volume (TIV)	1373.12 (117.94)	1407.84 (157.45)
WMH (ml)	3.30 (5.41)	8.58 (9.32)
WMH/TIV (%)	0.24 (0.40)	0.60 (0.64)

Means and standard deviations are indicated for all continuous variables. Proportional values are indicated for gender and number of APOE ε4 carriers. Group differences were calculated with independent-sample -tests or tests (gender and APOE genotype). Note: means significant when corrected for multiple comparisons ().