Cluster locations showing a significant interaction effect between the low and high depressive symptom score groups with the mean cluster fALFF response plotted against the MÅDRS-SIGMA score for broadband, slow-4 band, and slow-5 band (green represents low depressive symptom score group, blue represents high depressive symptom score group, and bands along regression line represent the 95% confidence interval). (a) Broadband: left insula. (b) Broadband: left superior temporal. (c) Slow-4: left thalamus. (d) Slow-4: right caudate. (e) Slow-5: left cerebellum. In the high depressive symptom group, high response from these regions was associated with an increased depressive symptom score. The low depressive symptom group showed no significant association between these regions and depressive symptom score. All brain images are shown in neurological convention.