Clinical Study
The Effect of Combined Patching and Citalopram on Visual Acuity in Adults with Amblyopia: A Randomized, Crossover, Placebo-Controlled Trial
| | Age/sex | AME VA logMAR | FFE VA logMAR | Type | AME refraction | FFE refraction | Strab | Stereo (arc/sec) | Suppression | History | BDNF | First treatment |
| | P1 | 43/F | 1.00 | 0.00 | Aniso | -0.25 | +6.00/ | | Nil | Full | Patching age 7 | Val66Met | Placebo | | P2 | 32/M | 1.20 | -0.04 | Mixed | +9.75 | -0.25 | Exo12Δ, hyper 11Δ | Nil | Full | Surgery 14 yrs, patching and spectacles 10-12 yrs | Val/val | Active | | P3 | 47/M | 0.64 | -0.10 | Mixed | Plano/ | +1.75 | Eso 10Δ | Nil | Full | Surgery 7 yrs | Val/val | Placebo | | P4 | 19/F | 0.34 | -0.04 | Aniso | +3.75/ | +0.50/ | | 60 | Intermittent | Detected 11 yrs patching and VT | Val66Met | Active | | P5 | 19/M | 1.00 | 0.00 | Strab | +4.50/ | +3.50/ | Eso 6Δ | Nil | Full | Spectacles and patching in childhood | Val/val | Active | | P6 | 30/M | 0.10 | -0.08 | Strab | Plano/ | -2 | Exo 20Δ | Nil | Full | Surgery 2 yrs, patching in childhood | Val/val | Active | | P7 | 44/M | 0.34 | 0.00 | Mixed | +5.25/ | +1.75/ | Exo 12Δ | Nil | Full | Surgery 2 and 10 yrs, spectacles until 15 yrs old | Val/val | Active |
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AME: amblyopic eye; FFE: fellow fixing eye; VA: visual acuity; exo: exotropia; eso: esotropia; hyper: hypertropia; aniso: anisometropic; strab: strabismic/strabismus; VT: vision training; BDNF: brain-derived neurotrophic factor.
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