Research Article

Central Plasticity of Cutaneous Afferents Is Associated with Nociceptive Hyperreflexia after Spinal Cord Injury in Rats

Figure 2

False color plots of CTM neurograms and percent changes 6 weeks after T10 hemisection spinal cord injury. CTM neurograms were recorded with 20 (1 Hz, top 4 plots) or 50 (5 Hz, bottom 4 plots) stimulations at a DCN level (either T6, T8, T12, or L1) at either ipsilateral (left) or contralateral (right) side to the side of CTM recoding (blue boxes). Each row (stimulation number) within each plot represents a color-scaled CTM response (see Figure 1) averaged in normal () and injured () animals for 200 milliseconds (ms) from each stimulation onset. The first stimulation in the train is the top row, and the last stimulation is the bottom row within each plot. Each box on the left diagrams (“changes”) displays only significant percent changes of early and late responses (see time windows in Figure 1) in animals with T10 hemisection injury (purple boxes) relative to normal controls (one sample -test, with large effect size, Cohen’s ) at each spinal level. Red color of boxes represents significant increase where darker red means greater extent of increases than lighter red, and the number of asterisks reflects the darkness of red color for black and white prints. There was no decreased response after SCI.