Central Plasticity of Cutaneous Afferents Is Associated with Nociceptive Hyperreflexia after Spinal Cord Injury in Rats

Figure 4

Spatial distribution of A and C fiber central projections from DCNs in the spinal cord of an uninjured normal control and an injured animal 6 weeks after T10 hemisection. CTB⁺ A fibers (green dots) and IB4⁺ C fibers (red dots) from T7 and T13 DCNs were identified as immunoreactive particles and overlaid on dorsal horn diagrams to show distribution profiles in terms of laminar, medial/lateral, and dorsal/ventral locations (see also Figure 3(a)). Representative projections were displayed on rostral (-) and caudal (+) cross sections to the dorsal root entry zone (DREZ) of the 4 mm spinal cord tissue block analyzed from a normal (left two columns) and an injured (right two columns) animal. Images for the normal control animal were adopted and modified from the previous publication [20].