Research Article
Widespread Striatal Delivery of GDNF from Encapsulated Cells Prevents the Anatomical and Functional Consequences of Excitotoxicity
Figure 4
Performance in all the cylinder, placing, and stepping tests is significantly impaired at 2 and 4 weeks following intrastriatal injections of QA. In contrast, performance on each of these tests is preserved, in a dose-related manner, by EC-GNDF implants with the higher dose-treated animals performing comparably to presurgery levels (preimplantation and prelesion). ; ; .
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