M2 Macrophages as a Potential Target for Antiatherosclerosis Treatment

Figure 3

M2 polarization pathways. The JAK-STAT pathway and Akt-p18-mTOR-LXR pathway are recognized as the main two pathways leading to M2 macrophage polarization. TSC1/2 was involved in the Akt-p18-mTOR-LXR pathway and affects macrophage polarity.