Hypertension and Its Impact on Stroke Recovery: From a Vascular to a Parenchymal Overview
Table 2
Summary of focal stroke models in the rodent. MCAO: middle cerebral artery occlusion; MT: mechanical thrombectomy; ET-1: endothelin-1; IC: internal capsule.
Model type
Transient/permanent
Topography
Standard neurological scores
Morbidity
Reproducibility
Translational approach
References
Intraluminal suture MCAO model
Permanent Transient
Large infarct Cortical and subcortical (according to the duration of ischemia)
Highly impaired
High
Moderate
No craniectomy Conflicting data in the literature: model of malignant ischemic stroke versus regain of interest with MT for ischemia/reperfusion models