HMG-CoA Reductase Inhibitors Attenuate Neuronal Damage by Suppressing Oxygen Glucose Deprivation-Induced Activated Microglial Cells

Figure 5

Rosuvastatin and atorvastatin increased LDLR expression in hypoxic BV2 cells. (a) OGD damage decreased the level of LDLR immunoreactivity in BV2 microglia. (b) Numbers of DAPI-positive cells are expressed as ratios to the C group (%). (c) Numbers of LDLR/DAPI-positive cells are expressed as ratios to the C group. Values shown are expressed as the , and between-group differences were assessed by one-way ANOVA followed by LSD test (homogeneity of variance was determined); . vs. the C group, vs. the C group, vs. the C group, vs. the OGD group, and vs. the OGD group.

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