Enhanced Visual Attentional Modulation in Patients with Inherited Peripheral Retinal Degeneration in the Absence of Cortical Degeneration
Table 2
Ophthalmological characterization of the participants from the patients’ and controls’ groups and for the patients from visual field extent subgroups (RPsvf and RPlvf) and the disease onset age subgroups (RPeo and RPlo). The visual field and onset age subgroups only differ in the visual field extent and in the age of onset of the disease, respectively. Results showed a severe decrease of patients’ visual acuity, visual field extent, and average retinal thickness when compared to the control group (RNFL thickness was unchanged).
Visual parameters
Eye
RP group ()
Control group ()
Visual field extent
Disease age of onset
RPsvf subgroup
RPlvf subgroup
RPeo subgroup
RPlo subgroup
Visual acuity (logMAR)
LE
0.22 (0.20)
0.00 (0.11)
0.26 (0.22)
0.18 (0.30)
0.14 (0.21)
0.30 (0.20)
RE
0.30 (0.18)
0.00 (0.11)
0.30 (0.12)
0.40 (0.18)
0.35 (0.21)
0.30 (0.12)
Retinal thickness (μm)
LE
228.00 (51.00)
288.50 (21.50)
214.50 (60.50)
242.60 (57.00)
226.50 (61.75)
242.00 (60.00)
RE
243.00 (54.00)
285.00 (20.75)
225.50 (54.25)
245.00 (44.00)
235.50 (48.25)
245.00 (55.00)
RNFL thickness (μm)
LE
100.00 (33.00)
94.50 (10.50)
92.00 (33.00)
101.00 (37.00)
96.00 (26.25)
100.00 (52.00)
RE
99.00 (26.50)
95.00 (17.25)
99.50 (46.50)
99.00 (17.00)
95.50 (16.50)
108.00 (47.00)
Visual field deficit volume (dB·deg2)
LE
1349.00 (501.50)
30.00 (24.25)
1294.50 (509.50)
1414.00 (837.00)
1526.50 (806.00)
1240.00 (353.00)
RE
1349.00 (544.50)
27.50 (44.00)
1290.50 (539.50)
1402.00 (1070.00)
1505.50 (870.50)
1233.00 (267.00)
Visual field extent (~diameter; deg)
LE
14.50 (14.25)
48a
8.00 (2.13)
21.50 (24.00)
19.75 (15.88)
8.00 (13.50)
RE
13.00 (16.75)
48a
8.25 (3.00)
21.00 (27.50)
17.00 (21.13)
8.50 (14.50)
Onset age onset (years)
—
—
Disease duration (years)
—
—
Data are median (interquartile range) and ; RP = Retinitis Pigmentosa; RPsvf = small visual field; RPlvf = large visual field; RPeo = early onset; RPlo = late onset; LE = left eye; RE = right eye; RNFL = retinal nerve fiber layer; logMAR = logarithm of Minimum Angle of Resolution. aVisual field extent for the control group is the maximum diameter tested during the static perimetry (48 deg).
