Research Article

Differential Relationship between Microstructural Integrity in White Matter Tracts and Motor Recovery following Stroke Based on Brain-Derived Neurotrophic Factor Genotype

Table 1

Characteristics of participants according to BDNF genotype.

Groups value
Val ()Met ()

Female, (%)6 (35.3)13 (31.7)0.767
Age, (range) (yr) (35-80) (33-80)0.492
Stroke lesion type,
 Right : left hemisphere10 : 720 : 210.777
 Cortical : subcortical : corticosubcortical lesion1 : 12 : 47 : 31 : 30.557
 Volume of stroke lesion (cm3)0.082
FMA-UE scores at T1, (range) (0-62) (0-61)0.750
FMA-UE scores at T2, (range) (7-66) (4-66)0.599
Absence of MEP response at T1, (%)10 (58.8)26 (63.4)0.773

: the number of patients; : ; BDNF: brain-derived neurotrophic factor; FMA-UE: Fugl-Meyer assessment, upper extremity score; MEP: motor evoked potential; Met: carriers of methionine allele of BDNF genotype; T1: two weeks after stroke onset; T2: three months after stroke onset; Val: patients with valine homozygotes of BDNF genotype.