Neural Plasticity

Research Article

Differential Relationship between Microstructural Integrity in White Matter Tracts and Motor Recovery following Stroke Based on Brain-Derived Neurotrophic Factor Genotype

Table 2

Partial correlation adjusted by age, stroke lesion volume, and severity of initial motor impairments between tract-fractional anisotropy at T2 and upper limb motor impairments at T2 in patients with the valine homozygotes of the BDNF genotype (Val group) and methionine allele carriers of BDNF genotype (Met group).


		Val group	Met group
Tracts		FMA-UE at T2	FMA-UE at T2

CST	Ipsilesional	0.338	0.469
	Contralesional	-0.382	0.276
	Ratio	0.254	0.259
M1PMv	Ipsilesional	-0.388	0.286
	Contralesional	-0.599	0.092
	Ratio	0.134	0.228
CC		-0.372	0.407

Each cell represents correlation coefficients (). FMA-UE: Fugl-Myer assessment, upper extremity score; CC: corpus callosum; CST: corticospinal tract; FA: fractional anisotropy; M1PMv: intrahemispheric corticocortical connection from primary motor cortex to ventral premotor cortex; T1: two weeks after stroke onset; T2: three months after stroke onset; , .