Neural Plasticity / 2020 / Article / Fig 2

Research Article

Toll-Like Receptor 2 Attenuates Traumatic Brain Injury-Induced Neural Stem Cell Proliferation in Dentate Gyrus of Rats

Figure 2

Immunofluorescence (IF) microphotographs in the dentate gyrus (DG) of the DG in sham and TBI groups at different time points. (a) BrdU-labelled NSCs (red fluor), expression of TLR2 (green fluor), cell nuclei (blue fluor), and BrdU+/TLR2+/DAPI+ cells indicated that TLR2 expression in labelled proliferating cells was possible NSCs; (b) BrdU+ cells showed the proliferation of NSCs in the DG during different time points posttrauma. BrdU+ cells were more in the TBI group than that in the sham group (), and numbers of these cells were significantly different among different time points posttrauma (#); (c) numbers of BrdU+/TLR2+ cells indicated that the expression of TLR2 was quite different in proliferating cells of the DG among different time points posttrauma. There were more BrdU+ cells in the TBI group than that in the sham group (), and the numbers of these cells are obviously different among different time points posttrauma (#). Scale bar: 50 μm; data is shown as .
(a)
(b)
(c)

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.