Research Article
Hyperoside Attenuate Inflammation in HT22 Cells via Upregulating SIRT1 to Activities Wnt/β-Catenin and Sonic Hedgehog Pathways
Figure 3
Hyperoside inhibits LPS-induced HT22 cell apoptosis and inflammation through SIRT1. The expression of SIRT cells was measured by western blotting (a). The expression of Bcl-2, Bax, and caspase-3 in HT22 cells was measured by western blotting (b). The HT22 cell apoptosis rate was measured by flow cytometry assay (c). The level of IL-1β, IL-6, IL-8, and TNF-α mRNA in HT22 cells was measured by qRT-PCR (d). was considered significant compared to control (); # was considered significant compared to LPS (#); ▽ was considered significant compared to LPS+HYP (▽).
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